In 2008, isolates represented by non-susceptibility ...

Microbiology resistance status and trends of evolution Klebsiella pneumonia isolates in the university hospital in Greece: Inefficiency karbapenemy and increasing resistance to kolistyn IC Neonakis, G. Samonis, H. Messaritakis, S. Baritaki, A. Georgiladakis, S. Maraki, D . Spandidos

Department of Clinical Bacteriology, Parasitology, zoonoses and geographical medicine

Faculty of Medicine internal University Hospital of Heraklion, and

Department of Laboratory Medicine, School of Medicine University of Crete, Heraklion, Greece >> << Chemotherapy 2010; 56:448-452 (DOI: 10. 1159/000 320 943)

Keywords abstract background: In connection with its increase, no susceptibility rate

Klebsiella pneumonia was one of the most problematic pathogens microorganisms. Methods: The level of resistance at 25 K. pneumonia drugs

isolates from a university hospital in Greece and trends over 2 years were examined. Results: statistically significant increase in non-susceptibility rates were found for almost all antimicrobial agents examined. In 2008, isolates represented by non-susceptibility to aminoglycosides rates 50 and quinolones 60. Currently 1 in 10 isolates are not susceptible to kolistyn. In addition, isolates tolerant to imipenem were almost double between 2007 (29) and 2008 (50). Among imipenem-resistant isolates, 1 of 4 also resistant to kolistyn. Conclusion: The effectiveness karbapenemov was compromised and increase resistance kolistyn quickly and steeply. Copyright 2010 S. Karger AG, Basel

Author Contact Ioannis K. Neonakis, MD, MPH, Ph.D.

Department of Clinical Bacteriology, Parasitology,

zoonoses and Geographic Medicine University Clinic of Heraklion

Voutes, GR71201 Heraklion (Greece)

Tel. +30 2810 392 599 strattera 40mg Fax +30 210 7252 922, E-Mail

article was reported: 1 January 2010

accepted after revision: June 20, 2010

Published online: November 18, 2010

Number of pages: 5 Number of Figures: 1, Number of Tables:

2, Number of References:

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